ExoSeq® GI

Who is it for?

• Colorectal cancer diagnosed before the age of 50, or families meeting the Amsterdam II criteria
• More than 100 polyps (FAP) or 10–100 polyps (AFAP / MUTYH)
• Diffuse gastric cancer with a family history of signet ring cell carcinoma (CDH1)
• Pancreatic cancer at a young age or in more than one family member

A selection of the 336 genes is listed below as examples.

Technical details

Method

Whole exome sequencing (NGS), targeted gene panel analysis

Sample

Blood in EDTA tubes (2 × 3 ml)

Turnaround time

6 weeks

Output

Clinical report + FASTQ and VCF files

Included with your report

• Report with clinical interpretation
• Raw data (FASTQ) and variant file (VCF)
• Recommendations for family testing

How does the process work?

1. 1
   Leave your request

   Choose the test, or let your physician request it on your behalf. If you are not sure which test fits, we decide together.

2. 2
   We call you

   Our team calls within 1 working day to confirm the request, the sample type (blood or tumour tissue) and your appointment time.

3. 3
   Sample collection

   A blood sample is taken at Akasya Partner Clinics in a few minutes. For tissue tests, the pathology block is collected by courier.

4. 4
   Report and review

   The report is ready in 1–6 weeks depending on the test (stated on each test page), sent to your physician and reviewed with our consultant physicians.