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Oncology Code: CNACT-701

CanAct® X Solid

CanAct® X Solid is a comprehensive genomic profiling (CGP) test that analyses 523 genes at the DNA level and 55 genes at the RNA level in tumour tissue. It detects point mutations, small insertions/deletions, copy number variations, translocations, microsatellite instability (MSI) and tumour mutational burden (TMB) from a single sample, in a single analysis.

CanAct® X Solid
Sample
Paraffin-embedded tumour tissue (FFPE)
Turnaround time
3–4 weeks
Method
DNA + RNA NGS
Ordering
Following physician assessment
This test is performed on tumour tissue in a paraffin block. A tissue sample is not something the patient can bring in themselves; it is obtained from the pathology department. We plan the process together with your oncologist.

Who is it for?

  • Patients diagnosed with a metastatic or advanced solid tumour
  • Cases where targeted therapy or immunotherapy options are being explored
  • Investigation of treatment resistance mechanisms
  • Matching to suitable clinical trials

Genes analysed

523 genes

Genes analysed for RNA fusions

55 genes
ABL1AKT3ALKARAXLBCL2BRAFBRCA1BRCA2CDK4CSF1REGFREML4ERBB2ERGESR1ETS1ETV1ETV4ETV5EWSR1FGFR1FGFR2FGFR3FGFR4FLI1FLT1FLT3JAK2KDRKIF5BKITKMT2AMETMLLT3MSH2MYCNOTCH1NOTCH2NOTCH3NRG1NTRK1NTRK2NTRK3PAX3PAX7PDGFRAPDGFRBPIK3CAPPARGRAF1RETROS1RPS6KB1TMPRSS2

Technical details

Method
DNA + RNA next-generation sequencing (CGP)
Sample
Formalin-fixed, paraffin-embedded (FFPE) tumour tissue
Turnaround time
3–4 weeks
Reported
Point mutations, indels, CNVs, translocations/fusions, MSI, TMB
Variant classification
AMP/ASCO/CAP levels of evidence; FDA and NCCN references
Laboratory
CAP-accredited; certified to ISO 15189, ISO 9001 and ISO 27001

Included with your report

  • Clinically actionable biomarkers
  • Therapies the tumour may benefit from, and therapies it may be resistant to
  • Suitable clinical trials (with NCT numbers)
  • MSI status and TMB value
  • A physician-friendly report format, with optional counselling

How does the process work?

  1. 1
    Leave your request

    Choose the test, or let your physician request it on your behalf. If you are not sure which test fits, we decide together.

  2. 2
    We call you

    Our team calls within 1 working day to confirm the request, the sample type (blood or tumour tissue) and your appointment time.

  3. 3
    Sample collection

    A blood sample is taken at Akasya Partner Clinics in a few minutes. For tissue tests, the pathology block is collected by courier.

  4. 4
    Report and review

    The report is ready in 1–6 weeks depending on the test (stated on each test page), sent to your physician and reviewed with our consultant physicians.

Last updated:

Your genes are ready to talk.

Send us your request; we will call you, answer your questions and find the day that suits you best, together.

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